A Personal Journey With Chronic Spontaneous Urticaria

December 22, 2025

What causes hives on arm of patient

Chronic spontaneous urticaria (CSU) is often dismissed as “just hives” — but for patients and families, the impact can be life-altering. Featured by the Dermatology Times, Certified Nurse Practitioner Amanda Marsh-Caldwell of U.S. Dermatology Partners in Warrensburg, MO shares a deeply personal journey with CSU told through the eyes of both a mother and dermatology clinician. She highlights the emotional toll, treatment challenges, and why timely access to effective therapies matters.

In dermatology, we often talk about chronic spontaneous urticaria (CSU) in terms of mast cell activation, guideline-based treatment steps, and response rates. What we don’t always capture is the real burden: the sleepless nights, the unpredictability, the relentless trial and error of treatments. I understood the science as a dermatology clinician, but I didn’t fully grasp the lived experience until my own child was diagnosed.

 

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